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Tuesday, 26 April 2016 17:30

Tapeworms

tapeworm Equine tapewormsPhoto kindly provided by University of Liverpool Diagnosteq Lab

Most horses are exposed to tapeworm and they may become infected at any age. Light infection is common, and if limited, is unlikely to produce any clinical signs. In severe cases, infection can cause physical damage to the gastrointestinal tract resulting in the following clinical signs:

  • Diarrhoea
  • Dull Coat
  • Poor Growth
  • Intermittent Colic Episodes
  • Poor performance
  • General Lethargy
  • Ulceration of the GI lining
  • Colic
  • Obstruction
  • Rupture
  • Anaemia
  • Un-thriftiness

Diagnostics & Treatment of Tapeworm

We know from the tapeworm life cycle that when the tapeworm sheds its eggs they are dispersed in a segment of its body called the proglottid.

If the proglottid remains intact then no eggs will be found in the faeces in spite of the horse being infected. As a result, tapeworm eggs are rarely detected in faecal egg counts (FEC) even if the horse is infected.

ELISA Antibody Test

The ELISA antibody test can be utilised to check for tapeworm exposure. This test is convenient and simple to carry out as saliva samples can be utilised.

Tapeworm - treatment options and resistance

  FenbendazolePyrantelIvermectinMoxidectinPraziquantel
Anoplocephala spp. Not indicated Effective when used at double the “normal” roundworm dose
Resistance status undetermined – reports of resistance emerging from the US
Not indicated Not indicated Resistance suspected but generally appears to remain highly effective – reports of resistance emerging from the US

Source: Canter Guidelines

Remains effective for indicated use

Resistance emerging or suspected

Some resistance reported – FECRT should be performed

Resistance common – should only be used with supportive FECRT results

Not indicated for use for treatment

Monday, 25 April 2016 21:08

LARGE STRONGYLES (Large Redworms)

large strongylesLarge Strongyles (aka Large Redworms)There are three major species of Large Strongyles, which are Strongylus vulgaris, S edentates, and S equinus. Of these, the most common is Strongylus vulgaris.

Thankfully the large Redworm (Strongylus vulgaris) is no longer as common

The eggs are ingested by the horse and once hatched, they burrow into the walls of the gastrointestinal tract.

Migration through the blood vessels occurs, until mature, and can cause massive internal damage before they return to live in the intestinal wall. Large Strongyles are blood feeders and they ingest mucosal plugs as they move through the intestine. Anaemia can result from this blood loss.

LargeStrongyleCycle L

Heavy infection can result in:

  • Ulceration of the GI lining
  • Obstruction
  • Rupture
  • Anaemia
  • Un-thriftiness
  • Weight loss
  • Diarrhoea
  • Colic

Large Strongyles can be extremely dangerous to the horse. However, low resistance levels mean that control is relatively straightforward.

Large strongyles- treatment options and resistance

  FenbendazolePyrantelIvermectinMoxidectinPraziquantel
Strongylus spp (adults) Assumed to remain effective Assumed to remain effective Assumed to remain effective Assumed to remain effective Not indicated

Source: Canter Guidelines

Remains effective for indicated use

Resistance emerging or suspected

Some resistance reported – FECRT should be performed

Resistance common – should only be used with supportive FECRT results

Not indicated for use for treatment

Monday, 25 April 2016 20:58

SMALL STRONGYLES (Small Redworms)

(cyathostomes spp)

small strongylesCyathostomes spp infestation in small intestine

The most common worm is the Small Redworm (cyathostomin spp) which can lead to encysted small Redworm disease if untreated.

When ingested, the larvae burrow into the lining of the intestines. They either develop and re-emerge to continue the life cycle, or stay in a state of hibernation in the intestinal lining-hypobiosis.

Hypobiotic larvae can all emerge at once causing severe damage to the intestinal wall which can cause weight loss, diarrhoea, shock and death.

small strongyles life cycle

The Typical Life Cycle of Small Strongyles

  1. The horse ingests grass which has stage L3 larvae on it.
  2. The larvae enter the large intestinal mucosa. There it either undergoes hypobiosis (similar to hibernation) and emerges as L4 later or immediately emerge as L4. There is a high damage risk of large numbers of encysted L4 emerging from mucosa at same time
  3. The L4 larvae develop and lay eggs
  4. These eggs pass out in faeces
  5. The eggs on the faeces develop first into L1, then into L2 and finally into L3 larvae
  6. The larvae move onto the grass
  7. The horse ingests grass and the cycle starts again
 

Small strongyles- treatment options and resistance

  FenbendazolePyrantelIvermectinMoxidectinPraziquantel
Cyathostomins Adults Resistance is common
Should only be used with supportive FECRT results
Resistance reported FECRT should be performed to confirm efficacy Complete resistance considered uncommon but shortened egg reappearance periods are now a common finding Shortened egg reappearance periods are now being reported and resistance recently reported in the UK Not indicated
Encysted larvae 5-day course
Resistance is common and use for 5 consecutive days does not overcome it
Should only be used with supportive FECRT results
Not indicated Not indicated No reports of resistance atthe encysted larval stages1 Not indicated

1 Larvicidal efficacy of moxidectin ranges from about 20 to 70% against Early Third Stage Larvae (EL3s), and 50-80% against developing larvae (late L3s and mucosal L4s) (Nielsen, 2022).
Source: Canter Guidelines

Remains effective for indicated use

Resistance emerging or suspected

Some resistance reported – FECRT should be performed

Resistance common – should only be used with supportive FECRT results

Not indicated for use for treatment

Monday, 25 April 2016 20:57

LUNGWORMS

(Dictyocaulus arnfieldi)

Lungworm can cause coughing and respiratory difficulty in horses, although they are relatively uncommon. Lungworm is more common in donkeys and risk increases when horses and donkeys graze together

Horses become infected by eating the worm larvae from the pasture. The larvae will then move to the lungs, where they become adult. These adults, living in the airways, can cause obstruction leading to coughing and breathlessness. The adults lay eggs which are coughed up and swallowed to then be passed out in the droppings; thus continuing the cycle.

 

Lungworm - treatment options and resistance

  FenbendazolePyrantelIvermectinMoxidectinPraziquantel
Dictyocaulus arnfieldi Not indicated Not indicated Effective against adults andlarval stages1 Not indicated Not indicated

1 Not all authorised products have this indication
Source: Canter Guidelines

Remains effective for indicated use

Resistance emerging or suspected

Some resistance reported – FECRT should be performed

Resistance common – should only be used with supportive FECRT results

Not indicated for use for treatment

Monday, 25 April 2016 20:41

PINWORMS

(Oxyuris Equi)

pinwormsAdult pinworm emerging to lay eggs

The pinworm lives in the large intestine and passes out of the anus to lay its eggs.

The pinworm is a grey/white worm with a long tail, which tapers to a point. While the male is significantly smaller, the female pinworm can reach up to 20cm in length.

Although pinworms live in the large intestine and colon, the adult worm emerges at night to lay eggs on the skin around the rump. After laying her eggs, the female pinworm will then return inside the rectum. A female pinworm can lay up to 60,000 eggs per day.

The pinworm can cause severe itching around the anus which can occasionally lead to self-trauma.

pinwormsPinworms cause irritation to the horse. Look out for rubbing of the rear end against fences, which can result in damage around the anus.

Biting and licking of hindquarters may also be observed. There are no eggs on faecal examination. However, eggs may be seen in a gelatinous mass around the anus.

Sellotape can be gently pressed on the skin around the anus to pick up eggs and if present a number of treatments can be used.

No eggs will be found on a faecal worm egg count as the adult female worm crawls out of the anus to lay eggs.

Pinworm - treatment options and resistance

  FenbendazolePyrantelIvermectinMoxidectinPraziquantel
Oxyuris equi Considered the most effective treatment

Clinical responses may still be poor
Considered effective

Clinical responses are often poor
Resistance suspected but not yet confirmed in the UK

Clinical responses are often poor
Resistance suspected but not yet confirmed in the UK

Clinical responses are often poor
Not indicated

Source: Canter Guidelines

Remains effective for indicated use

Resistance emerging or suspected

Some resistance reported – FECRT should be performed

Resistance common – should only be used with supportive FECRT results

Not indicated for use for treatment

Monday, 25 April 2016 20:30

BOTS (STOMACH WORMS)

bots eggsBot eggs

The bot (stomach worm) is not a worm but the larvae of Gasterophilus flies.

The adult horse bot fly emerges a during the summer or fall season. After the fly emerges from the pupa, it quickly finds a mate, lays the eggs on the horse's coat and, on grooming, the eggs make their way to the mouth where they hatch in mouth as larvae.

Over winter the larvae burrow into the stomach lining (where they spend 8-10 months) and are then passed out via the faeces and will hatch in the summer.

Heavy infestation may result in trauma and ulceration of the stomach lining.

Disease is also caused by the larvae in mouth. Larvae here create borrowing holes, which in turn become infected. The 3rd stage larvae are passed in the faeces and over winters to develop the following summer.

Infected horses can often show no signs, which is why treatment should be given over the winter months to kill them.

 

bots-gasterophilus fly larvaeBots fly larvaePhoto kindly provided by University of Liverpool Diagnosteq Lab

 

Bots - treatment options and resistance

  FenbendazolePyrantelIvermectinMoxidectinPraziquantel
Gasterophilus
spp
Not indicated Not indicated Effective
Specific treatment is not considered necessary
Less effective than ivermectin Not indicated

Source: Canter Guidelines

Remains effective for indicated use

Resistance emerging or suspected

Some resistance reported – FECRT should be performed

Resistance common – should only be used with supportive FECRT results

Not indicated for use for treatment

Monday, 25 April 2016 19:58

LARGE ROUNDWORMS (ASCARIDS)

ascarids parascaris equorumLarge Roundworms (ascarids)Photo kindly provided by University of Liverpool Diagnosteq Lab

Ascarids, (also known as roundworms) are parasites which are mainly a problem to foals. However, small numbers can also be carried by adults.

The adult worms are very large and can be up to 40cm in length. Once the larvae of this parasite are swallowed, they pass through the gut wall, via the liver to the lungs. Heavy infestations can cause coughing as the larvae travel through the lungs.

Adult worms can cause intestinal impaction. They pose a considerable threat to young horses and their developing immune systems, and they have to potential to kill by triggering colic. Even if a young horse escapes colic, a heavy ascarid burdened young horse will appear depressed and its normal growth will be affected.

The most common ascarid to infect horses is Parascaris equorum.The eggs laid by the large females pass out into pasture protected by a tough shell which equips them well for survival.  They can withstand drying conditions and even freezing; waiting for that moment when a passing horse ingests them with grass.

Large Roundworms - treatment options and resistance

  FenbendazolePyrantelIvermectinMoxidectinPraziquantel
Parascaris spp. Some resistance now reported FECRT should be performed Some resistance now reported FECRT should be performed Resistance is common Should only be used with FECRT Resistance is common Should only be used with FECRT Not indicated

Source: Canter Guidelines

Remains effective for indicated use

Resistance emerging or suspected

Some resistance reported – FECRT should be performed

Resistance common – should only be used with supportive FECRT results

Not indicated for use for treatment

Monday, 25 April 2016 18:32

Advice For Providing In Feed Medication

In-Feed medication tips from Bimeda Equine, ao you & your horse can get back in the saddle.

Monday, 25 April 2016 15:13

Recocam

meloxicam 20mg/ml

Monday, 25 April 2016 15:12

Oxytobel

oxytocin 16.6 µg

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Bimeda Equine is proud to promote best practice targeted worming regimes to help protect both today’s horses and future generations.

To find out more about best practice, visit the CANTER website and review their guidelines.


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For full product information, including contra-indications, see the data sheet, or see the SPC which can be found on the VMD website

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